Department of Cell Biology

Selected Publications

For a full list of lab publications visit PubMed

Hancock ML, Nowakowski DW, Role LW, Talmage DA, Flanagan JG. Type III neuregulin 1 regulates pathfinding of sensory axons in the developing spinal cord and periphery. Development. 2011 Nov;138(22):4887-98. doi: 10.1242/dev.072306. PMID: 22028026

Coles CH, Shen Y, Tenney AP, Siebold C, Sutton GC, Lu W, Gallagher JT, Jones EY, Flanagan JG, Aricescu AR. Proteoglycan-specific molecular switch for RPTPσ clustering and neuronal extension. Science. 2011 Apr 22;332(6028):484-8. doi: 10.1126/science.1200840. Epub 2011 Mar 31. PMID: 21454754

Tcherkezian J, Brittis PA, Thomas F, Roux PP, Flanagan JG. Transmembrane receptor DCC associates with protein synthesis machinery and regulates translation. Cell. 2010 May 14;141(4):632-44. doi: 10.1016/j.cell.2010.04.008. Epub 2010 Apr 29. PMID: 20434207

Shen Y, Tenney AP, Busch SA, Horn KP, Cuascut FX, Liu K, He Z, Silver J, Flanagan JG. PTPsigma is a receptor for chondroitin sulfate proteoglycan, an inhibitor of neural regeneration. Science. 2009 Oct 23;326(5952):592-6. doi: 10.1126/science.1178310. Epub 2009 Oct 15. PMID: 19833921

Chen Y, Mohammadi M, Flanagan JG. Graded levels of FGF protein span the midbrain and can instruct graded induction and repression of neural mapping labels. Neuron. 2009 Jun 25;62(6):773-80. doi: 10.1016/j.neuron.2009.05.023. PMID: 19555646

Osterfield M, Egelund R, Young LM, Flanagan JG. Interaction of amyloid precursor protein with contactins and NgCAM in the retinotectal system. Development. 2008 Mar;135(6):1189-99. doi: 10.1242/dev.007401. Epub 2008 Feb 13. PMID: 18272596

Flanagan JG. Neural map specification by gradients. Curr Opin Neurobiol. 2006 Feb;16(1):59-66. Epub 2006 Jan 18. Review. PMID: 16417998

Hansen MJ, Dallal GE, Flanagan JG. Retinal axon response to ephrin-as shows a graded, concentration-dependent transition from growth promotion to inhibition. Neuron. 2004 Jun 10;42(5):717-30. PMID: 15182713

Osterfield M, Kirschner MW, Flanagan JG. Graded positional information: interpretation for both fate and guidance. Cell. 2003 May 16;113(4):425-8. Review. PMID: 12757702

Brittis PA, Lu Q, Flanagan JG. Axonal protein synthesis provides a mechanism for localized regulation at an intermediate target. Cell. 2002 Jul 26;110(2):223-35. PMID: 12150930

Lu Q, Sun EE, Klein RS, Flanagan JG. Ephrin-B reverse signaling is mediated by a novel PDZ-RGS protein and selectively inhibits G protein-coupled chemoattraction. Cell. 2001 Apr 6;105(1):69-79. PMID: 11301003

Flanagan JG, Cheng HJ. Alkaline phosphatase fusion proteins for molecular characterization and cloning of receptors and their ligands. Methods Enzymol. 2000;327:198-210. No abstract available. PMID: 11044984

Hattori M, Osterfield M, Flanagan JG. Regulated cleavage of a contact-mediated axon repellent. Science. 2000 Aug 25;289(5483):1360-5. PMID: 10958785

Vanderhaeghen P, Lu Q, Prakash N, Frisén J, Walsh CA, Frostig RD, Flanagan JG. A mapping label required for normal scale of body representation in the cortex. Nat Neurosci. 2000 Apr;3(4):358-65. PMID: 10725925

Feldheim DA, Vanderhaeghen P, Hansen MJ, Frisén J, Lu Q, Barbacid M, Flanagan JG. Topographic guidance labels in a sensory projection to the forebrain. Neuron. 1998 Dec;21(6):1303-13. PMID: 9883724

Cheng HJ, Nakamoto M, Bergemann AD, Flanagan JG. Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map. Cell. 1995 Aug 11;82(3):371-81. PMID: 7634327

Cheng HJ, Flanagan JG. Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases. Cell. 1994 Oct 7;79(1):157-68. PMID: 7522971

Cheng RW, Yusof F, Tsui E, Jong M, Duffin J, Flanagan JG, Fisher JA, Hudson C. Relationship between retinal blood flow and arterial oxygen. J Physiol. 2016 Feb 1;594(3):625-40. doi: 10.1113/JP271182. Epub 2015 Dec 30. PMID: 26607393