For a full list of lab publications click here
Coles CH^, Shen Y^, Tenney AP, Siebold C, Sutton GC, Lu W, Gallagher JT, Jones EY*, Flanagan JG*, Aricescu AR* (2011) Proteoglycan-specific molecular switch for RPTPsigma clustering and neuronal extension. Science 332:484-8. [^co-first, *co-corresponding]
Hancock ML, Nowakowski DW, Role LW, Talmage DA*, Flanagan JG* (2011) Type III Neuregulin 1 regulates pathfinding of sensory axons in the developing spinal cord and periphery. Development 138:4887-98. [*co-corresponding]
Tcherkezian, J*, Brittis, PA*, Thomas, F, Roux, PP, Flanagan, JG (2010) Transmembrane receptor DCC associates with protein synthesis machinery and regulates translation. Cell 141:632-44. [*co-first]
Shen, Y*, Tenney, AP*, Busch, SA, Horn, KP, Cuascut, FX, Liu, K, He, Z, Silver, J, Flanagan JG. (2009) PTPsigma is a receptor for chondroitin sulfate proteoglycan, an inhibitor of neural regeneration. Science 326:592-6. [*co-first]
Chen, Y, Mohammadi, M, Flanagan, JG (2009) Graded levels of FGF protein span the midbrain and can instruct graded induction and repression of neural mapping labels. Neuron 62:773-780.
Osterfield, M, Egelund, R, Young, LM, and Flanagan, JG (2008) Interaction of amyloid precursor protein with contactins and NgCAM in the retinotectal system. Development 135:1189-99.
Flanagan, JG. (2006) Neural map specification by gradients. Curr. Op. Neurobiol. 16:59-66.
Hansen, MJ, Dallal, GE, Flanagan, JG. (2004) Retinal axon response to A ephrins shows a graded, concentration-dependent transition from growth promotion to inhibition. Neuron 42:717-730.
Osterfield, M, Kirschner, MW, and Flanagan, JG. (2003) Graded positional information: interpretation for both fate and guidance. Cell 113: 425-428.
Brittis, PA, Lu, Q, and Flanagan, JG. (2002) Axonal protein synthesis provides a mechanism for localized regulation at an intermediate target. Cell 110:223-235.
Lu, Q, Sun, EE, Klein, RS, and Flanagan, JG (2001) Ephrin-B reverse signaling is mediated by a novel PDZ-RGS protein and selectively inhibits G-protein coupled chemoattraction. Cell 105:69-79.
Flanagan, JG, Cheng, H-J (2000) Alkaline phosphatase fusion proteins for molecular characterization and cloning of receptors and their ligands. Meth. Enzymol. 327: 198-210.
Hattori, M, Osterfield, M, and Flanagan, JG (2000) Regulated cleavage of a contact mediated axon repellent. Science 289: 1360-1365.
Vanderhaeghen, P, Lu, Q, Prakash, N, Frisen, J, Walsh, CA, Frostig, RD, Flanagan, JG (2000) A mapping label required for normal scale of the body representation in the cortex. Nature Neuroscience 3: 358-65.
Nakamoto, M, Cheng, H-J, Friedman, GC, McLaughlin, T, Hansen, M, Yoon, C, O'Leary, DDM, Flanagan, JG (1996) Topographically specific effects of ELF-1 on retinal axon guidance in vitro and retinal axon mapping in vivo. Cell 86: 755-66.
Cheng, H-J, Nakamoto, M, Bergemann, AD, Flanagan, JG (1995) Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map. Cell 82: 371-81.
Cheng H-J, Flanagan JG (1994) Identification and cloning of ELF-1, a developmentally-expressed ligand for the Mek4 and Sek receptor tyrosine kinases. Cell 79:157-68.